Sentence examples for manipulation of immunity from inspiring English sources

The strategies employed by parasites fall into two main categories: (i) avoidance of the immune response, and (ii) manipulation of immunity to favour establishment and maintenance of infection.

Direct manipulation of immunity in order to tear apart its relationship with condition is a particularly powerful approach to demonstrate the causal relationship between a fitness component (e.g. growth, survival) and immunity [4], [5].

These mechanistic insights into manipulation of host immunity by a parasite product have implications for the design of anti-inflammatory therapeutic drugs.

Therefore, like T3SS, T6SS have been implied to play a role in manipulation of host immunity.

Therefore, the study and manipulation of antimalarial immunity seems difficult in the absence of any information concerning the effects of helminths on this response.

It is therefore not surprising that parasites have evolved counter measures, with evasion and manipulation of host immunity a widespread practice seen in both vertebrate and invertebrate hosts (Schmid-Hempel 2008).

Importantly, immunity to tumour-associated antigens can be potentiated given proper identification and manipulation of immune-regulatory checkpoints restricting T cell function [ 47,48].

Increasing evidence suggests that both CD4+ and CD8+ T cells play a critical role in cancer immunosurveillance and anti-tumor immunity, and manipulation of these immune cells to recognize and eradicate tumor cells is a promising strategy for treating patients with invasive and metastatic cancers.

Experiments manipulating RBC densities (for example with Erythropoietin or phenylhydrazine), and manipulations of host immunity (through vaccination, drugs and infective doses) will undoubtedly prove important next steps in furthering our understanding of the ecological and evolutionary processes underlying parasite transmission strategies.

This indicates that C. jejuni has evolved specific immune evasion strategies; manipulation of host mucosal immunity to counteract the evasion strategies is a future therapeutic challenge.

Numerous preclinical studies also suggest that various manipulations of innate immunity can modulate Aβ and tau proteostasis and other pheno types in preclinical models.