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We know from established experiments in neurobiology that many experiences described by the faithful, including visions of god, can be replicated in the laboratory with relatively simple manipulation of brain function.
Pharmacological manipulation of brain steroidogenesis has proved a useful strategy in elucidating the influence of local neurosteroid production upon shaping inhibitory transmission in specific neuronal populations.
Pharmacological or experimental manipulation of brain structures has been performed in an attempt to modulate the pigs' learning or memory abilities but, compared with the number of rodent studies, relatively few such studies have been performed.
New mutant mouse models allow gene-based manipulation of brain function relevant to sequential patterns, but no current animal model of spontaneous OCD-like behaviors has so far been reported to exhibit sequential super-stereotypy in the sense of a whole complex serial pattern that becomes stronger and excessively rigid.
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The findings, published recently in the journal Behavioural Brain Research, suggest that manipulations of brain activity could be an effective way of obtaining truthful responses from defendants and criminal suspects, raising more ethical questions about the application of neuroscience technologies in the legal profession.
Several laboratories are exploring post-stroke manipulations of brain plasticity following experimental injury in terms of the timing and type of intervention.
By combining TMS with concurrent fMRI (Bohning et al., 1999; Baudewig et al., 2001; Ruff et al., 2006, 2009; Sack et al., 2007; Bestmann et al., 2008a, b; Driver et al., 2009), we were also able to examine the impact of our TMS manipulation on brain activity during task performance.
Evidence that surgical manipulation of the brain could calm patients first emerged in the late 1880s, when Swiss physician Gottlieb Burkhardt, who supervised an insane asylum, removed parts of the brain cortex in patients suffering from auditory hallucinations and other symptoms of mental illness (symptoms later defined medically as schizophrenia).
Alternatively we instead focus on the creation of a simple, versatile aerator designed to allow maintenance and manipulation of acute brain slices and potentially other tissue in a multi-well cell culture plate.
A promising approach could be a more direct manipulation of involved brain regions by excitation or inhibition through transcranial magnetic stimulation (TMS).
Moreover, the feasibility of external manipulation of the brain, even on complex behaviors, opens different possibilities for neural rehabilitation.
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CEO of Professional Science Editing for Scientists @ prosciediting.com