Sentence examples for manipulation of activity from inspiring English sources
For technical reasons having to do with the relative ease of manipulation of activity levels in vitro, most previous studies involving externally imposed alterations of activity were performed on developing neurons in culture systems.
We tested how responses of the model putative excitatory neurons are affected by manipulation of activity of PVs or SOMs.
Furthermore, the slowing of movement was probably caused through manipulation of activity in the primary motor cortex, the site of the maximal current density.
The results of the PCA and clustering analyses based on 8 spontaneous activity-derived parameters suggest that no current injection or other experimental manipulation of activity is needed to properly determine the phenotypic trajectory of dopaminergic cells.
Several characteristics grant aptamers potential superior to that of therapeutic antibodies, including increased binding affinity, in vitro manipulation of activity and/or stability, less immunogenicity or toxicity, and scalable chemical production.
It is therefore important to resolve whether aberrant patterns of CS activity occur in animal models of ataxia and dystonia, whether potential abnormalities in the delays of ensemble activity can be correlated to deficits in locomotion and posture, and to what extent manipulation of activity patterns can influence limb and trunk movements.
However, there is little information concerning homeostatic mechanisms following in vivo manipulations of activity levels.
Three sets of results were in general agreement with previous studies on homeostatic responses to in vitro manipulations of activity.
In contrast, three sets of results sharply differed from previous reports on homeostatic responses to in vitro manipulations of activity.
Future studies will be needed to examine how different interneuronal types respond to various in vivo manipulations of activity.
The presence of multiplicative (or proportional) synaptic scaling, observed after manipulations of activity in cultures, suggested that homeostatic synaptic plasticity scales neuronal output without modifying the relative strength of individual synapses [2], [44].
