Sentence examples for manipulation in zebrafish from inspiring English sources

This chapter focuses on the transgene manipulation in zebrafish by using recombinases.

This is due to ease of genetic manipulation in zebrafish, the aneuploid nature of cancers arising in zebrafish, and the capacity of these animals for high-throughput genetic and pharmacologic screens (Zhang et al., 2010; Zon and Peterson, 2005).

Giving the advantage of performing imaging, genetic and pharmacological manipulations in zebrafish, srn will be a useful tool to guide future analyses in human CDG IIc patients and contribute to a better understanding of the mechanisms responsible for this devastating disorder that affects nervous system and other organ development.

Although the experimental manipulations used in zebrafish and in the newt brain here are different from each other, and we cannot rule out the possibility that microglia could activate NSCs in the newt brain under certain conditions, our observations indicate that the two animal species embark on at least partially non-overlapping signaling mechanism during neuronal regeneration.

Furthermore, a popular morpholino oligonucleotide (MO) gene knockdown approach allows easy manipulation of gene activity in zebrafish [29].

Here, we used live imaging and manipulation of Fyn kinase function in zebrafish to study the dynamic regulation of myelin sheath number by individual oligodendrocytes in vivo.

Furthermore, manipulation of the level of pbx2 expression in zebrafish embryos resulted in a change in the timing of the onset of shh expression in pectoral fin primordia in a low percentage of embryos (see Fig. S4 and S6).

The conservation of TOR signaling pathway has been explored in zebrafish using both pharmacological manipulation and morpholino gene knockdown [67].

In the present study, we used a series of molecular, pharmacologic and genetic manipulations in mice and zebrafish to demonstrate that IP3Rs are involved in the local control of Ca2+ that is necessary to activate the calcineurin-NFATc signaling pathway required for cardiogenesis.

With the variety of tools available for transient genetic manipulation in rapidly developing embryos, researchers studying zebrafish can complete phenotyping assays in just a few days.

These findings of the pharmacological manipulations are consistent with an inhibitory role for 5-HT in aggression in zebrafish, as implied in studies with these compounds in other fish [ 46- 48].