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The principle of MHC class I manipulation in general can be used for other allogeneic cell and tissue-engineered transplants as well.
The strategies reviewed in this article are applicable to modification of DNA molecules of any size, including very large ones, and present powerful new avenues for DNA manipulation in general.
At week 8, 2 patients in the Tq group had flexion < 90 degrees that required forced manipulation in general anesthesia.
There would be much less value in testing hypothesis 'b' if a prior test had already established that there was no clinically important difference between spinal manipulation in general and general practice care.
T manipulation in general resulted in significant alterations in MYO of second-order mesenteric arteries, with T replacement decreasing MYO in SHR (P < 0.05) compared to CONT, T replacement increasing MYO, and CAST decreasing MYO in WKY rats (P < 0.001) compared to CONT rats.
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Yet there are secular voices opposing the technology too, in particular campaigners against genetic manipulations in general, such as Marcy Darnovsky of the Center for Genetics and Society.
Any interactive manipulation results in general in a non-replicable state.
Purposive sampling was used to identify the manipulations occurring in general and specialised clinical in-patient areas.
As the "default" view one acquires from the mid-esophagus, it requires the least amount of probe manipulation and is, in general, easiest to obtain.
But reflecting the state-of-the-art of the tools available for implementing the principle of community involvement to its full extent, it is also recognized that there is a need for better tools for collaborative ontology development and for manipulation of ontologies in general (Buffa et al. 2008).
In addition this study makes a contribution to the field of manipulation and medicine, in general, by highlighting the limited research and reference standards in this field.
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