Sentence examples for manipulating this pathway from inspiring English sources

Finally, by manipulating this pathway, we show that BM fibrillar structure influences egg chamber morphogenesis.

Recent data on the biochemistry of carotenogenesis and its regulation in vivo present the possibility of genetically manipulating this pathway in crop plants.

For these reasons, it will be essential to determine the identity of the other ligand or ligands that cooperate with myostatin, as only then will we be able to develop the best possible strategies for manipulating this pathway for the treatment of human diseases in which promoting muscle growth may be beneficial.

Manipulating this pathway using RNAi, dominant-negative and pharmacological approaches leads to a disruption of GABAAR clustering and decrease in the strength of synaptic inhibition.

Functional experiments in cultured cells and primary motor neurons demonstrate that manipulating this pathway by reducing the expression of a single upstream target, the negative phosphatidylinositol-3 kinase regulator phosphatase and tensin homology, promotes a marked pro-survival effect.

An experimental approach manipulating this pathway or directly inhibiting the immune activation would help to better understand why male tarantulas present a semelparous reproductive strategy while females are iteroparous.

Whether viruses can manipulate this pathway to improve their interaction with the host during the course of a natural infection and what the physiological implications would be are open questions.

Understanding the function of ESCRT-III in greater detail may suggest ways to manipulate this pathway to limit the replication of viruses or the degradation of membrane proteins.

The cytokine IL-15 and its receptor (IL-15Rα) were found perturbed in the pancreatic islets and serum of patients; of note, treatment with tofacitinib to manipulate this pathway resulted in diabetes reversal in NOD mice, providing rationale from both nPOD specimens and experimental models for testing this as a new therapeutic option in clinical trials [ 44 ].

Rice geneticist Ko Shimamoto, the lead author, foresees manipulating this genetic pathway, which could extend the growing season or provide ornamental flowers year-round.

If they can, then perhaps her ideas about manipulating this growth pathway to cure baldness wouldn't be so hair-raising.