Sentence examples for manipulating these pathways from inspiring English sources

However, owing to their regulatory, catalytic, and structural complexities, manipulating these pathways poses considerable challenges.

By rationally reprogramming and manipulating these pathways, unnatural metabolites containing enhanced structural features that were otherwise inaccessible can be obtained.

Recent successes to introduce non-native carbon fixation pathways into heterotrophic hosts offer novel platforms for manipulating these pathways in genetically malleable organisms.

In wild type dopamine neurons, manipulating these pathways resulted in a decrease in acute desensitization and larger GIRK currents, suggesting that D2S and D2L receptor regulation may operate in parallel in wild type neurons.

Overall, our findings indicate that there is no ideal set of typical alterations when co-opting natural utilization pathways for titratable control and suggest design rules for manipulating these pathways to advance basic genetic studies and the metabolic engineering of microorganisms for optimized chemical production.

Using the tools of synthetic biology allows us to manipulate these pathways and produce the desired compounds.

"It sparks hope that if we can manipulate these pathways... it may facilitate chemoprevention or early detection --although he cautions that that possibility is years from fruition.

Furthermore, the ability to manipulate these pathways is now possible and will allow the engineering of crops with improved sulphur acquisition and utilization traits.

Common compounds used to manipulate these pathways include metformin, resveratrol and rapamycin.

As a result, there is considerable interest in the therapeutic potential of selective small molecules to manipulate these pathways in order to ameliorate disease [ 4].

Combined with methods to validate and manipulate these pathways, this resource greatly expands molecular insight into neuronal regulation of body weight, and may be useful for devising therapeutic strategies for obesity and eating disorders.