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Results from our modelling suggest that the feedback from manipulating the host is sufficient to acquire and maintain both the behavioural manipulation (zombie) and liquefaction (gooey) traits.
Although these projects may initially appear to have no common threads, they are all related in that they focus on deliberately manipulating the host?s response in order to elicit a predetermined, desired biological outcome.
Therefore, VipA may play a role in manipulating the host secretion pathway in macrophages [11].
Salmonella activates the PKB/Akt1 pathway to prevent maturation of SCV into destructive phagolysosomes, thus manipulating the host for its own survival [14].
SPI genes thus encode many virulence factors that are involved directly in manipulating the host system and may be responsible, at least in part, for the host specificity of different S. enterica serovars.
Besides their role in nutrition, these are thought to play an important role in manipulating the host reproductive system through reproductive parasitism, i.e., feminization of genetic males, parthenogenesis and cytoplasmic incompatibilities, thereby increasing the frequency of infected females in the host population [77] [82].
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Data from our laboratory suggests that the S isolate has evolved methods of manipulating the hosts T regulatory cell arm of the immune response[ 9], and the responses of key antigen presenting cells to parasite antigens[ 10].
A second approach aims to manipulate the host immune response by including immunologic molecular adjuvants as part of the vaccine including T cell costimulatory molecules, cytokines, and chemokines.
The bacterial type III secretion system is a specialized machine that injects effectors into eukaryotic cells to manipulate the host cell physiology.
Pathogenic E. coli species including EPEC, EHEC and Shigella spp. use specialized T3SSs to deliver effector proteins into their mammalian hosts in order to manipulate the host response in their favor.
Some of these changes may not result solely from host responses, but actively induced changes by parasites/parasitoids to manipulate the host to acquire some benefit (e.g. parasite/parasitoid survivorship or dispersal ability).
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prompting the host
influencing the host
handing the host
manipulating the pursuit
manipulating the quantity
manipulating the value
manipulating the paper
manipulating the weather
manipulating the information
manipulating the puppet
manipulating the map
manipulating the market
manipulating the jaw
manipulating the microbiome
manipulating the system
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