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The field was inaugurated in 1994 by Len Adleman of the University of Southern California, who wrote a paper explaining how he had solved a simple route-planning problem by manipulating strands of DNA in a test tube.Clever stuff.
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"We have manipulated strands to insert what we want it to be in the document, regardless as to whether or not it's appropriate".
An inactive object, however, such as a small pebble enmeshed in the web, produces a different response: the spider manipulates the strands of the web, locates the object, and cuts away the filaments surrounding it so that the object drops to the ground.
This paper reported the results of an experiment that solved a computational problem, the Hamiltonian Path Problem, solely by manipulating DNA strands in test tubes.
"In embroidery, the needle is manipulating a single strand of yarn through a fabric substrate, similar to a 'through hole' on a microfluidic chip.
The Metropolitan Opera presented Thomas Adès's 2004 opera "The Tempest," adapted from the Shakespeare play, in a new production by Robert Lepage that showed Prospero as a frustrated opera house impresario trying to manipulate the stranded inhabitants of his island.
Two classes of topoisomerases reverse supercoiling by creating breaks in one (type I) or both strands of duplex DNA (type II), manipulating the cleaved strand with respect to the other (intact) strand and attaching the strands of DNA together.
Potentially, one could manipulate the degree of exposure (dose) by manipulating the stringency of the intervention.
The closely held Photonic, based in Sydney, Australia, makes devices used to manipulate and control light as it travels on hair-thin strands of glass.
By manipulating the selective release of each foot from complementary strands of DNA on the DNA tile, the movement of the walker could be controlled.
In addition, DNA methyltransferase 1 (DNMT1) can translocate to the mitochondria and catalyze mitochondrial DNA (mtDNA) methylation, thereby manipulating the expression of transcripts from the heavy and light strands of mtDNA [ 17].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com