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This data set consists of images of BT549, human breast cancer cells, that have been manipulated to express the protein phosphatidylinositol 4-kinase III beta (PI4KIII β).
Surprisingly, despite good documentation of the role of LABs as adjuvants in mucosal immunogenicity [ 25, 26], these GRAS status bacteria have yet to be manipulated to express TRP-2 for both therapeutic and prophylactic settings.
As in mice manipulated to express V600EBraf in the lung (Dankort et al, 2007) and melanocytes (Dhomen et al, 2009), we show here that V600EBraf induces oncogene-induced senescence (OIS) in the intestine following an initial wave of hyperplasia.
In tomato plants, a PR-5 protein was detected in plastids where it specifically accumulated in chloroplast starch granules when plants were manipulated to express systemic acquired resistance [ 41].
Experiments using human retinal pigment epithelial (HRPE) cells manipulated to express the individual system A subtypes revealed Km values for SNAT1, SNAT2 and SNAT4 of 0.89, 0.39, 6.7 mM, respectively [12,13,15].
Furthermore, results from reconstitution experiments where rank-/ cells were manipulated to express RANK mutants lacking the TRAF6-binding region provided evidence for the involvement of TRAF6 in RANK-directed cytoskeletal organization and resorption function of osteoclasts [ 16].
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Similar results have been obtained with other tumour cell lines genetically manipulated to over express FasL, and rejection is associated with the induction of marked inflammation with extensive neutrophil infiltration [ 7].
In general, it is a comparative static model based on total differentiation of a system of equations but manipulated to be expressed in terms of elasticities rather than slopes.
Explants can be experimentally manipulated to over-express or under-express various proteins and features within cells can be tagged fluorescently enabling their visualization using low-light widefield and confocal microscopy [ 10, 11].
In addition to the P value, FDR was manipulated to determine differentially expressed genes [ 56].
Despite such encouraging advances, the application of hESC-derived cardiomyocytes for basic developmental research and large-scale applications, such as high throughput screening, toxicology testing and large animal studies, has been hindered by their poor yield from the heterogeneous hESC cultures and the difficulty of manipulating hESCs to express uniform levels of reporter constructs.
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