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Interestingly, all of the genetic models in which we manipulated the activity of downstream targets of TORC1 were starvation sensitive; flies overexpressing a constitutively active S6K, 4E-BP nulls, and flies with reduced expression of Atg5 were more sensitive to starvation than their controls.
We also manipulated the activity of BMP signalling in vitro.
They manipulated the activity of shoal mates by changing the water temperature (in cold water, the activity was reduced).
We then applied our approach to an experimental system of metabolic engineering in Lactococcus lactis (Hoefnagel et al. 2002) where the investigators had manipulated the activity of a specific enzyme to achieve a desired metabolic effect.
To investigate how depolarization of transmembrane potential of cells in the neural crest's environment influences its function in vivo, we manipulated the activity of the native glycine receptor chloride channel (GlyCl).
Similar(55)
A team of neuroscientists at University College London has developed a new way of simultaneously recording and manipulating the activity of multiple cells in the brains of live animals using pulses of light.
By manipulating the activity of individual genes, Jarvis eventually hopes to determine which ones are essential for vocal learning.
We believe that the reported approach paves the way for manipulating the activity and stability of other TiO2-supported metal nanocatalysts.
Develop new technologies that can record and manipulate the activity of large numbers of neurons at the resolution of individual calls, in any region of the brain.
One area that has just come to the fore involves optogenetic techniques, which allow neuroscientists to selectively manipulate the activity of specific neurons using light.
Previous studies have established that transcranial direct current stimulation (tDCS) is a powerful technique for manipulating the activity of the human cerebral cortex.
Related(20)
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