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Rodent models have been widely used because these animals can be taught complex alcohol-related behaviors that can then be manipulated and evaluated by pharmacological, genetic, and electrophysiological techniques [reviewed by Lovinger and Crabbe (2005) and Stuber et al. (2010)].
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Aimed at correlating the high SOCS3 and SOCS1 expression to the resistance to apoptosis of psoriatic keratinocytes, we manipulated their expression and evaluated the effects on cytokine-induced cell death.
We studied neurogenesis in a prion disease model as this would provide a basis for manipulating neurogenesis and evaluating its impact on both behaviour and pathology.
We manipulated floral guide size and evaluated visitation frequency.
The measurements of temperature, flow rate, applied voltage to the heater and pressure drop in the duct are recorded and manipulated to evaluate Nusselt number and friction factor.
Thereafter, using the colon cancer cells line, we manipulated the expression of UbcH10 and evaluated the cell cycle profile and cellular proliferations.
As a result, a mouse with virtual controllers for 3D manipulating has been discussed and evaluated in conjunction in several previous studies (Chen et al. 1988) (Khan et al. 2008).
The advent of reverse genetics technology has revolutionized the study of RNA viruses, making it possible to manipulate their genomes and evaluate the effects of these changes on their biology and pathogenesis.
Since the micro-fragmented fat is autologous, minimally manipulated and widely used in other surgical fields (i.e. lipofilling), safety was assessed just by evaluating local adverse events, such as fever, infections, and excessive swelling of the knee.
"He is not easily manipulated and assertive".
He felt manipulated and betrayed.
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