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We had cramped spaces and a tiny desk area that left little room to manipulate the mouse".
The ability to manipulate the mouse germline affords numerous approaches toward understanding the complexities of this disease, possibly providing accurate preclinical models for therapeutic and diagnostic advances.
The solution was involved changing the placement of semaphores that improperly protected shared data, allowing the kernel to schedule tasks that would interrupt the serial communication being done within another task and manipulate the mouse parameters.
Jobs's commitment to the mouse-driven graphical user interface helped make personal computing possible, but his zeal for the system also blinded him to the fact that a typist is hampered each time the hand abandons the keyboard to manipulate the mouse.
They accomplished this by using mouse embryonic stem cells to manipulate the mouse genome at the very start of development.
The ability to manipulate the mouse genome has allowed the evaluation of genetic alterations potentially involved in human prostate tumorigenesis, as well as the identification and preclinical validation of molecular targets for potential pharmacological intervention [13].
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Manipulating the Mouse Embryo: A Laboratory Manual 3rd edn.
Linden's original research involves glow-in-the-dark neurons in mouse brains he manipulates the mouse's DNA, allowing its neural pathways to shine under blue light like psychedelic poster patterns but he has written at length about the science of touch and has become widely expert in the field.
With the development of ever more sophisticated methods for manipulating the mouse genome, new p53 models are on the horizon, which should deliver advances that will provide not only important mechanistic insights but also discoveries of great clinical relevance.
I am now convinced that hours manipulating the mouse wore down the cartilage in a couple of my shoulder bones, strained some of the small connective muscles in the area and led to the diagnosis I got recently from Jonas Rudzki at Washington Orthopedics and Sports Medicine: arthritis in the acromioclavicular joint and rotator cuff tendinitis.
Due to the difficulties of manipulating the mouse preimplantation embryo, there has not been any study using securin degradation to study SAC activity in this system.
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