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He will use bacterial genetics to manipulate the gut bacterial metabolism and use pre-clinical mouse models to study how the metabolism of our gut bacteria affects host metabolism, host intestinal immunity, and IBD development.
Novel probiotics and prebiotics designed to manipulate the gut microbiota for improving health outcomes are in demand as the importance of the gut microbiota in human health is revealed.
Certainly, attempts to manipulate the gut microbiota via FMT may prove to have unintended adverse consequences.
Arguably, diet is among the most easily controlled factors that can potentially manipulate the gut microbiota.
Strategies to manipulate the gut microbiota towards a healthier community structure are actively being investigated.
These findings have led to attempts to manipulate the gut microflora of fish through pre- and probiotics to improve fish health and growth [ 30].
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Our results open the intriguing possibility that modifying LPL activity through ANGPTL4, central to fat storage regulation, by manipulating the gut flora could be one important mechanism by which various interventions may modulate body fat storage.
At present, on the basis of what has recently been published for acetaminophen, we cannot exclude the possibility that gut bacteria may be the principal target for drugs, and that by manipulating the gut flora in the drug treatment, the outcome can be improved (33).
There are two ways to manipulate the microbes in the gut (collectively, the microbiome): by consuming live cultures of bacteria called probiotics; or by ingesting certain types of sugar molecules, known as prebiotics, that nurture growth of these bacteria.
"Studies like this provide new leads" about how one might manipulate the microbes in the gut to prevent or treat allergies.
However, experiments to manipulate the composition of the gut community in A. glabripennis and other phloephagous and xylophagous beetles to demonstrate the impact of disruption of select microbes on fitness and digestive physiology have been impeded by the difficulty of rearing these insects on anti-microbial free artificial diet.
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CEO of Professional Science Editing for Scientists @ prosciediting.com