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This diversity may also apply to the manner in which, and the extent to which, nanomaterials may be able to manipulate the fate of different ESC lines.
Other EBV proteins manipulate the fate of host proteins by accelerating or decelerating their degradation through the ubiquitin-proteosome system, while simultaneously decelerating their own ubiquitination and degradation [ 50, 67].
However, regulatory mechanisms underlying the differentiation of ESCs into specific cell types are poorly defined, and thus understanding its mechanism might allow us to manipulate the fate of stem cells for stem cell-based therapies.
The process of cell differentiation is an important issue in stem cell biology and understanding its mechanism might allow us to manipulate the fate of primitive cells thus opening novel modalities for stem cell-based therapies.
By examining the entire p53 gene network instead of only the p53 gene itself, we identified regulatory relationships among genes that manipulate the fate of human skin cells [17], [18].
The process of cell differentiation is a central issue in stem cell biology and understanding its mechanism might allow us to manipulate the fate of stem cells opening novel avenues for stem cell-based therapies.
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Sofia Jean Gomez is a formidable Athena, scheming along with Hera, queen of the goddesses (played drolly by Lisa Tejero), to manipulate the fates of the would-be heroes.
It has been established that he manipulated the fate of Yemen for the sake of his vengeful agenda, by supporting the coup staged by the Houthis, and by corrupting the Yemeni army.
Answering these questions will not only offer huge insights for the mechanistic understanding of the establishment and maintenance of PSCs, but also help the development of safe and efficient technologies to manipulate the cell fate for regenerative medicine.
In addition to providing a "liquid-like" tubular microenvironment to understand one-dimensional self-assembly process of ES cells, this alginate hydrogel microstrand system also offers an alternative way to manipulate the stem cell fate-decision using bioengineered microenvironments.
The plant host of R. leguminosarum manipulates the cellular fate of its symbionts using antimicrobial-like peptide factors [ 102].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com