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The results show that CRISPRi is a feasible method to manipulate genes in Klebsiella pneumoniae.
The finding might eventually allow scientists to manipulate genes in rice and other crops to enhance production.
Finally, the development of genetic tools to introduce and manipulate genes in macrolide-producing organisms has led to a significant understanding of the genetic and biochemical bases of biosynthesis of these complex molecules.
However, the difficulties of performing large scale functional genomic studies in vector mosquito species include the lack of highly efficient genomic tools to manipulate genes in mosquitoes as well as the lack of mutants.
New technologies are adding to our ability to manipulate genes in the mouse and indeed to contemplate human gene therapies.
The key approach used in these analyses is to manipulate genes in a controlled fashion in animal models in order to elucidate the genes' function(s) in alcohol-related phenotypes.
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For years, scientists have been manipulating genes in animals to make improvements in neural performance, strength and agility, among other augmentations.
This is mainly because rapid and efficient genetic methods for manipulating genes in the brains of higher mammals had been poorly available.
Generation of this knowledge together with our ability to manipulate genes involved in mediating tolerance to various stressors including low temperature will lead to the development of cold-resistant genotypes.
Initially, these experiments were focusing on single genes and enzymes, aiming to manipulate genes directly involved in creating the product of interest (Tyo, 2008).
As outlined above, there is now an array of technologies to monitor and manipulate genes and cell types in Platynereis.
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