Sentence examples for manifold pathways of from inspiring English sources

Liver-specific SMAD4 (the common downstream mediator for all TGF-β superfamily ligands) knock-out mice exhibit marked iron accumulation and fail to increase hepcidin expression in response to TGF-β1, BMP-4, IL-6 or iron overload, suggesting a common role for SMAD4 in the manifold pathways of hepcidin regulation [14].

No coverage is given here on the manifold and complex relationship between pathways of NAD(P)+ utilization and on their impact on glutamine and glucose metabolism.

As the pathways of aggregation are manifold, good understanding of the mechanisms behind is essential.

The calculations provide information about the excited state manifold along pathways for activated decay of metal-to-ligand charge-transfer (MLC T excited states via metal-centered (MC) states for the two complexes.

They can be used to trigger expression or cleavage of a manifold of proteins.

Such observations illustrate the complex manifold actions of 4-HPR, which may cause cell death by mixed apoptosis/necrosis by both caspase-dependent and -independent pathways (DiPietrantonio et al, 1998; Maurer et al, 1999).

Commonly reorganized metastamiRs (upregulated and downregulated) across the manifold of metastatic tumors are further examined Ingenuity Pathway analysis, Target Scan, and miRBase to determine the gene targets.

More generally, manifold substantivalism asserts that the manifold M of local spacetime theories is the mathematical structure that represents spacetime.

A manifold number of indices for orthodontic assessment have been described [ 14].

(14 J) There are manifold definitions of the term AD or living will.

During the last few decades, manifold derivatives of EAs have been proposed.