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TGF-β signaling is manifested by way of TGF-β receptor activation and the canonical pathway involves the subsequent phosphorylation of receptor-associated Smad2 and Smad3 proteins which form complexes with Smad4.
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The fanfare surrounding the Duchess of Cambridge typically manifests by way of sartorial homage.
What this means in practice is that when one stops drinking, even for a day or two, the increased activity manifests itself by way of an eruption of anxiety, more severe than anything that came before.
Burge's reasoning applies beyond testimony as becomes manifest by way of the objection that if the intelligibility of the speaker's affirmation depends upon the inferential structure of the communication mechanism, then an impurely preservative mechanism would be required for understanding, contrary to Burge's claim of an a priori entitlement (Bezuidenhout 1998).
Genius is manifested by the quality of the product.
Yet for all of his criticisms of Buddhism, Jinsai explained, in one of the appendices to his Gomô jigi, that the best way to refute Buddhism and heterodoxies generally was not by means of debate, but instead by manifesting the Confucian way of ethical engagement with the world in daily practical activities.
Human dignity, understood in this rarefied way, is distinct from the common kind of dignity manifested by someone who responds to difficult circumstances in a dignified manner.
We are surely surprised to see it manifested in this way by these women".
The influence of the street network is manifested in two ways: by restricting the spread of crime to only occur along network connections, and by incorporating network metrics as a proxy for human activity.
And it's manifested in many way-s - one of those ways is through artistic expression.
It was a curiosity that manifested way beyond the then-corrugated stands of Aggborough.
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