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These cells were extremely aggressive after implantation as manifested by progressive growth in the pancreas, peritoneal dissemination, and distant metastasis to multiple organs, including the liver and lungs.
Microvasculopathy is consecutively causing a diffuse and chronic ischemic cardiomyopathy manifested by progressive left ventricular dysfunction and most probably fibrosis [20].
AD is manifested by progressive cognitive deterioration, memory loss, behavioural changes, and eventually dementia.
AD is considered to be one of the most prevalent forms of dementia in humans, the symptoms of which are manifested by progressive cognitive impairment.
OA is manifested by progressive degeneration of articular cartilage which is believed to be usually caused by articular cartilage erosion and chondrocyte damage [ 2].
As one of the major complications of DM, diabetic cardiomyopathy is manifested by progressive heart failure and a poor prognosis in DM patients [ 5, 6].
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Biliary atresia (BA) is known as an orphan disease of the newborn, which manifests by progressive inflammation of the extrahepatic biliary tract [ 1, 2].
It is manifested by rapidly progressive proximal muscle wasting starting around 3 years of age, culminating with respiratory insufficiency and cardiac failure that leads to premature death by the mid 20s.
In addition to a loss in muscle strength, Dysferlin −/− mice also exhibited a cholinergic deficit manifested by a progressive, frequency-dependent decrement in their compound muscle action potentials following repetitive nerve stimulation, which was observed in another Dysferlin mouse model but not in a Dysferlin-independent mouse model of muscular dystrophy.
This improved clinical, gross, and histopathological effects on the small intestine after WBI and AIR in AdRspo1-treated mice were physiologically manifested by a marked and progressive restoration of the normal absorptive function of the intestine, as measured by xylose absorption test.
Encephalopathy is manifested by motor delay, mental retardation, progressive cognitive decline, seizures, and feeding difficulties.
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manifested by ineffective
manifested by several
manifested by cognitive
manifested by Western
manifested by disorganized
manifested by numerous
manifested by consistent
manifested by increased
manifested by temporary
manifested by significant
manifested by erythematous
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manifested by normal
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