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Based on data from the general population, we hypothesized that more than 30% of dialysis patients 65 years or older would have visual impairment manifested by loss of visual acuity, depth perception, or contrast sensitivity.
Alzheimer's disease is commonly manifested by loss of memory and other intellectual abilities which often result in interference of daily life.
The disease is manifested by loss of brain myelin upon physiological stress.
Age-related changes in stem cells are manifested by loss of lineage specificity, failure self-renewal or/and senescence.
After achieving the CCyR, patients may suffer from disease progression manifested by loss of the CCyR (state 4) or they may die while in remission (state 2).
TBI is defined as traumatically induced physiological disruption of brain function, as manifested by loss of consciousness, memory impairment, alteration of mental state, and/or focal neurological deficits.
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Exposure of human chondrocytes and engineered cartilage to high concentration of BUT (>1 μg/ml) resulted in significant cytotoxicity, manifested by losses in cell viability and changes in cell morphology.
RA cachexia is manifested by losses of muscle and bone mass, resulting in part from augmented cytokine activity [ 4].
Podosome-associated diseases manifest by loss or gain of podosome functions and include genetic diseases affecting podosome components and various cancers where tumor cells ectopically express podosome equivalents (invadopodia).
The clinical course may suggest a significant early loss of motor neurons, as manifested by a loss of strength or failure to gain strength with development.
Between 20% and 40% of KIT/PDGFRA WT GISTs show loss of function of the succinate dehydrogenase complex (SDH), manifested by the loss of subunit B (SDHB) protein expression.
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