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To determine whether endothelial cell injury would be produced by factor(s) released into the fetal circulation, manifested by altered messenger RNA expression of nitric oxide synthase.
AY rats demonstrate altered hippocampal functioning as manifested by altered synaptic plasticity and cognition.
Changes in the elasticity of liver tissue are manifested by altered phenotype in hepatic cells.
Such changes in the CNS are often manifested by altered adult behaviour patterns [24], [25], [26].
These abnormalities include age dependent muscle degeneration, reduced mobility, defects in eye development as manifested by altered photoreceptor axon pathfinding, and a shorter life span.
Two forms of polymyositis following toxoplasmosis are known; an acute, responsive to antiprotozoal therapy and a chronic manifested by altered immune response and requiring treatment with steroids [ 10].
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In accordance, ATP depletion from boar sperm surface altered the integrity of sperm proteasomes, manifested by an altered proteasomal subunit migration on SDS-PAGE [24].
The BCRP mutations may induce conformational changes as manifested by the altered uptake rates of Mitoxantrone by BCRP in the presence of other competitive binding substrates that have a varying degree of affinities toward BCRP efflux.
The function of one or more of these systems is altered in the presence of disease or injury, and this may be clinically manifested by alterations in cognitive and motor function, physical fitness, habitual physical activity, and physical function.
This could have been associated with the stronger ontogenetic shift caused insect herbivory, which was manifested by premature flowering, altered plant architecture and accelerated leaf senescence.
Perinatal exposure to PCBs/dioxins in laboratory animals induces a decrease in plasma T4 levels without significantly altering the growth (Lein et al. 2007; Zoeller et al. 2000), and T3 levels remain within the normal range (Porterfield 2000), indicating that the toxicity of these chemicals does not manifest by altering blood TH levels.
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CEO of Professional Science Editing for Scientists @ prosciediting.com