Between 2007 and 2010 cases of an unknown infectious disease were reported in Henan and Hubei Provinces, China, with patients presenting gastrointestinal symptoms, chills, joint pain, myalgia, thrombocytopenia, leukocytopenia and some haemorrhagic manifestations, resulting in a case fatality rate of 12 30% [ 9 ].
By dissecting different elements in the two main disorder groups, anxiety and depression, and looking at their ranges, from mild to extreme manifestation, resulting in a more detailed, deeper understanding of psychiatric comorbidity with migraine.
The diagnosis of PTLD is often difficult, due to various manifestations resulting in late diagnosis.
Management of individuals with brucellosis is extremely complex owing to its wide spectrum of clinical manifestations, resulting in high initial treatment failure and significant risk of relapse (Buzgan et al., 2010; Franco et al., 2007; Pappas et al., 2006).
Since the SSc cohort was rather heterogeneous, the frequency of anti-topo I antibodies was determined for the distinct patient groups and disease manifestations, resulting in sensitivities and specificities for the serological identification of these clinical characteristics with reference to the SSc cohort (Table 2 and Table 3).
From a performance perspective and considering previous research has identified performance issues with GIS and DI [18], these clinical manifestation resulted in a longer time to complete the MSUM, but not distance covered in the 24 h, despite not reaching significance possibly due to large individual variations within group comparisons.
Diagnosis is often delayed due to oligosymptomatic manifestation resulting in valvular and perivalvular destruction or abscess formation [ 3].
Diagnosis was often delayed due to oligosymptomatic manifestation, resulting in symptoms associated with progressive prosthetic valve dysfunction leading to heart failure (62%) at the time of diagnosis.
This, coupled with its dramatic clinical manifestations, has resulted in a strong social stigma.
For example, concerns related to realistic financial or health stressors can be viewed as a manifestation of depression or anxiety, resulting in an unnecessary and ineffective treatment intervention.
Similarly, AS and PsA were associated with a variety of extra-articular manifestations that can result in a number of comorbid conditions.
