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In one case the clinical manifestations persisted and it was thus considered unsuccessful.
In one patient with severe CINCA (patient number 2), the clinical manifestations persisted along with the elevation of acute phase reactants, despite the previous increase of the dose to 300 mg every 6 weeks.
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'Granulomatous' manifestations may persist or even develop throughout the generalized disease stage, yet this stage is, per definitionem, associated with organ- and or life-threatening vasculitis manifestations.
If GVHD manifestations improved but persisted after 9 12 months, treatment with MMF was continued for another 9 12 months.
Existing models focus on predicting asthma exacerbations, which often represent a late manifestation of persisting loss of asthma control, and have low sensitivities and low positive predictive values [ 20– 20].
Fever was the only initial manifestation, and it persisted after 1 week of antibiotic therapy.
Further research, most appropriately population-based studies using clinical reviews, is required to better understand the natural history, pathogenesis and long-term impact of persisting manifestations following CHIKV infection.
Negative symptoms and behavioral manifestations improved, but auditory hallucinations persisted.
She shrugs off travelgate as "the first manifestation of an obsession for investigation that persisted into the next millennium".
These "costume dramas", as Dobson and Watson call them, have persisted across the centuries, their most recent manifestation probably being in David Starkey's BBC television documentary on Elizabeth in this quatercentenary year of her death.
The extra-renal manifestations of Fabry disease persist in patients receiving RRT [ 27].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com