dDisease manifestations defined based on SLEDAI-2K definitions.
Typical clinical manifestations, defined as any of microcephaly, chorioretinitis, SNHL or a combination of petechiae, hepatosplenomegaly and jaundice, were observed in 22.7% (15/66) of the infected newborns (table 1).
The patient information collected included: 1) gender; 2) age at inclusion in the study; 3) history of dry eyes/mouth and/or recurrent parotid enlargement assessed by the AECG questionnaire; 4) duration of subjective sicca symptoms; 5) symptoms/signs suggestive of disease-related extraglandular manifestations, defined according to previous studies, and 6) comorbidities and related treatments.
Addiction is a complex psychological and neurophysiological manifestation, defined in terms of drug-using behaviors.
Figure 1 shows the estimates obtained for the probability that untreated malaria would progress to severe malaria (including any manifestation defined by WHO), stratified by age and transmission intensity.
The BINKI study provided sufficient numbers of laboratory-confirmed infected contacts and the numbers reporting typical disease manifestation (defined as at least 2 weeks of coughing and one or more of the following: paroxysmal coughing, posttussive vomiting, inspiratory 'whooping'), for the age-groups 1 4, 5 9, 10 19, and 20 59 years only.
There was no association between consultations at a healthcare structure and the level of education of the caretaker, distance to that health structure, adequate knowledge by the caretakers of the manifestations that define severe diarrheal disease, or adequate understanding of the necessary preventive measures against diarrhea.
Ocular manifestations were defined as any ocular disease secondary to HZO.
Joint manifestations were defined if arthralgia or peripheral arthritis was observed on examination.
Disease manifestations were defined in each patient as present ever from disease onset to most recent visit.
