"manifest reduction" is correct and can be used in written English.
It is usually used to refer to a situation in which something is significantly reduced or decreased. For example: "The rise in fuel prices has led to a manifest reduction in the number of cars on the roads."
Their manifest reduction at 6- and 12-month follow-up coincides with the reduction in psychosis for all patients.
The ONH GFP+ cells also displayed a manifest reduction in Iba1 expression relative to untreated eyes (Fig. 2C), consistent with the microglial deactivation reported for minocycline in this model (Bosco et al., 2008).
Focal adhesion kinase staining on paraffin sections of the isolated tumours showed a manifest reduction in FAK protein levels in FAKflox/− tumours, indicating that in our model FAK is successfully deleted.
In summary, our data show that TLR4 signaling is important for the development of septic AKI and that treatment with a TLR4 inhibitor is able to reverse a manifest reduction in renal function caused by sepsis.
We recognise that the understanding of injury pathways, dose response relationships and effectiveness of interventions to control such exposures has led to manifest reductions in injury frequency and disability.
In the context of predictive coding, learning involves a more efficient suppression of sensory events, which is manifest by an apparent reduction in evoked responses, mediated by top-down predictions (which explain away bottom-up sensory afferents).
Auto-calibration of neural oscillations may manifest as reduction of maladaptive forms of asymmetry between the right and left hemispheres [14], in multiple lobes including regions likely to play a role for management of the sympathetic and parasympathetic divisions, respectively [17 19].
Thus these results demonstrate that although increased steady state levels of CUG-BP1 is sufficient to produce features of DM1, elevated CUG-BP1 levels may not be required for DM1 pathology to manifest, as reduction of CUG-BP1 levels does not correct the splice defects in DM1 myoblasts.
It was hypothesizing the using EHR IS will result in more accurate and informed admission decisions, which will manifest through reduction in single-day admissions and in readmissions within seven days.
Longer-term effects may manifest as reduction in regional brain volumes since brain areas with the highest energy demand will be most affected by a restricted energy supply and may be reduced in size.
However, although VHL inactivation in CCRCCs should lead to constitutive HIF activation and miR-210 upregulation, further loss of cell differentiation coupled with ongoing mutations may manifest with reduction in expression of genes such as miR-210.
