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It has been shown that regulatory T cells require activation through T cell receptor in order to manifest functional activity but thereafter are nonspecific, i.e. once these cells are activated 27, 28.
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Of those who do not, most manifest significant functional impairments in their relationships and at work [ 6].
The profiles of motifs and anti-motifs manifest the functional preferences and repudiations of the particular network.
We also found, not unexpectedly, that these four groups of genes with distinct disease and differentiation trajectories manifest distinct functional ontologies.
It is conceivable that the conditions under which the same cytokine would manifest differential functional activities (pathogenic vs regulatory) might be distinct, and these conditions have yet to be fully defined.
We hypothesized that compensated HF patients, despite having comparable LVSVs to healthy subjects, would manifest their functional LV impairment as less LV diastolic inflow KE preservation and a diminished percentage of the flow component that transits the LV in a single cardiac cycle.
Thus, the sequence variation exhibited by the E1 alleles is presumably manifested as functional variation in the gene products of these alleles.
In autism, this network abnormality manifests as functional underconnectivity between different cortical regions.
Geneset enrichment analyses revealed how those changes manifested within functional categories and gene families.
But in ageing individuals, it has been observed to have greater impact, manifesting in functional, psychological and social limitations.
A clerk with geriatrics training would have learned to assess and investigate further when a patient manifests unexpected functional decline.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com