ICU flow is a dynamic process affected by constraints manifesting in large blocking times, assignment differences and significant cost variance.
For these reasons, laboratory systems of unicellular organisms are increasingly used to develop and test theories about biological constraints, which manifest themselves at different levels of biological organization, from optimal gene-expression levels to complex individual and social behaviors.
To predict how climate change might affect future Mediterranean species presence and distribution and, as a consequence, community structure and ecosystem functioning, it is essential to have a broad knowledge of which climatic factors are constraining plant species physiological traits, and how these constraints are manifested temporally (Llorens et al. 2003).
Representatives of the prospective member nations masterfully achieved political consensus by both the absence of objectionable clauses and the inclusion of national constraints, as manifested in the Treaty of Maastricht.
A modest sample size at level 2 (77 classes) impairs the measurement model fit of teachers' work enjoyment, but using manifest variables to avoid these constraints would have simply ignored measurement errors.
The time-dependent boundary conditions manifested by the prismatic joint constraints are considered.
Recall that we formalize the problem as finding disjoint node sets that induce connected subgraphs in the constraint graph and manifest high internal similarity.
This includes even the basic emotions, which may well have an inborn neurological core but nevertheless manifest themselves only within the social constraints provided by cultural experience.
The reliability-based topology optimization (RBTO) is a powerful and promising methodology for finding the optimum topologies with the uncertainties being explicitly considered, typically manifested by the use of reliability constraints.
Additionally, increased variance in expression level may indicate that a gene is not critical [ 30], and therefore subject to less evolutionary constraint, which could theoretically manifest in an accelerated rate of protein change for genes with high expression variance.
