Despite having a single set of institutions, a centralised decision-making process, and an essentially homogeneous ruling class, the Japanese government is unable to act in response to the manifest challenges which confront it.
He discounted the notion there would be no bidders for the facility in spite of the manifest challenges facing the health care industry throughout the country.
Christian discounted the notion that there would be no takers for the center, in spite of the manifest challenges that face the health care industry, which many believe needs a complete overhaul, according to Adventist.
While the power of this approach is manifest, challenges still remain.
Taken together, these findings indicate that tumor suppressor functions of RB and p53 are particularly manifest when challenged by cellular stress.
In light of these studies, we questioned whether the combined loss of RB and p53 is sufficient to drive tumorigenesis, or if the tumor suppressor functions of these proteins are only truly manifest when challenged by exposure to therapeutic stress.
Keep Well was based, therefore, on a model of anticipating health needs before they become manifest (thereby challenging a reactive, episodic model of care provision) and delivering continuous, integrated, preventive care with the patient as partner [ 19, 22].
The authors demonstrated that the described genomic rearrangements on mouse chromosome 11 Dp11(1) or its reciprocal deletion Df11(1) alter the susceptibility to multiple disease relevant phenotypes, that are actually manifested when challenged by a 'second hit' (genetic or environmental) (Fig 1).
This is likely because the challenge manifest in these informatics is more fundamental, having to do with the ways in which institutions and organizations leverage technologies to assert knowledge politics "in ways that rely upon the differential influence and authority that is granted to particular forms of knowledge or representations" (Barnett 2011).
These numerical challenges manifest themselves in spurious temporal oscillations in second order finite volume discretizations with both arithmetic and harmonic averaging.
The Design Science Information System (DSIS), evolved from DSR approach is used in solving the ecosystem issues associated with multiple domains, in which the sustainability challenges manifest.
