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Lidon, F. C., Barreiro, M. G. & Ramalho, J. C. Manganese accumulation in rice: implications for photosynthetic functioning.
Whether manganese accumulation in auditory-related brain regions will be sensitive enough to detect differences between awake and freely moving animals with and without tinnitus or between groups with tinnitus produced by different means (noise, salicylate, blast wave, etc).
Iron overload, in contrast, reduces manganese accumulation in the brain and in other organs [ 20].
A similar manganese transporter, Smf2p, was found to be essential to manganese accumulation in yeast cells even though it does not locate at the cell membrane.
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Because Manganese uptake into the neurons is mediated by the same calcium channels [24], the presynaptic inhibition of olfactory receptor neurons would reduce the manganese uptake by these neurons and could explain the lower manganese accumulation we found in the OB of starlings stimulated with an odour.
For a given region of interest then, differences in manganese accumulation, measured non-invasively with MRI, reflect differences in neuronal activity during the period of manganese accumulation, before anesthesia and MR imaging [55].
We expected that the amount of manganese accumulation would be higher in the olfactory bulb when the birds perceived a biologically relevant odour like milfoil.
Individual cases of childhood Manganism [ 62] or epileptic seizures [ 63] have been linked to manganese exposure, while excessive manganese accumulation has been implicated in hepatocerebral syndrome [ 64].
Newete et al. (2016), showed that manganese accumulation increased with greater concentrations in the growth medium31.
Recessive mutations in SLC30A10 have been linked to a syndrome characterized by severe manganese accumulation, polycythaemia, neurological disturbances and liver complications (10, 30).
Manganese accumulation might be connected presumably with a photosynthetic apparatus.
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