Sentence examples for mandatory to demonstrate from inspiring English sources

Conduction of phase III trials remains mandatory to demonstrate treatment efficacy, but their endpoints and design are currently object of discussion.

According to the European law for products intended for use as a repellent on horses (recreational and sport horses), a field test is mandatory to demonstrate sufficient repellency of such a substance against the specific target fly species, but currently no agreed protocols are available for testing of potential repellents.

Such a mismatch not only limits the interpretation of these studies but also hinders future development of disease modifying therapies since biomarkers and biological endpoints are mandatory to demonstrate a putative neuroprotective effect of a drug.

Several steps are mandatory to demonstrate the causal relationship between a vector and a disease.

It is therefore mandatory to demonstrate that the lipofilling procedure in breast cancer patients does not increase the risk of local or distant cancer recurrences.

Mandatory requirements to demonstrate funding accountability and short-term results often lead to donors promoting a state of fragmentation and redundancy (Cassels and Janovsky, 1998; Hutton, 2002).

However, further studies are mandatory to establish this hypothesis.

For several years, the U.S. National Science Foundation has made it mandatory for grant applicants to demonstrate that their research will have an impact on society via the "broader impacts" criterion.

During the Weimar era, numerous physicians put forward arguments designed to demonstrate that a mandatory health insurance system, which necessarily involves economic and social policy, imperceptibly becomes a factor of socially standardized health care, which could compromise the Hippocratic ideal of care, and force physicians to make paradoxical choices in their daily practice.

In ITER, an accurate measurement of plasma current, with high reliability, is mandatory as this parameter is used to demonstrate licensing compliance with regulatory limits.

It is mandatory to carry out clinical studies to demonstrate the participation of renal dopaminergic system in pathological contexts involving impaired sodium excretion as nephrotic syndrome or insulin resistance states.