Pay freezes, mandatory furloughs and the effects of sequestration were all testing their already low morale.
Tissue collection in trials is mandatory so the effect on outcome of different tumour phenotypes and BRCA mutation can be explored.
Stable corticosteroids doses were mandatory because of the effect on p450 cytochrome (Vecht et al, 2003), and the compliance to response evaluation criteria in neuro oncology (Macdonald et al, 1990).
Long-term clinical studies are mandatory to elucidate the effect of treatment in the management of AD.
The present paper discusses the design, characterization and in vivo evaluation of glyceryl monostearate nanoparticles of Olanzapine, an atypical antipsychotic drug for acute schizophrenia treatment, during which hospitalization is mandatory and adverse effects are at its peak.
Considering the importance of evolution to the study of both biodiversity and to issues such as health and agriculture, it is mandatory to lessen the effects of sociocultural traits on the learning process.
Further prospective trials are mandatory to confirm the effects observed in this single case and to discriminate gemcitabine-induced from cetuximab-associated response.
Comparison of old and new curriculum using some measurement tools is mandatory to observe the effects of innovations.
It is therefore mandatory to study the effects of previous TB history on LTBI, including through clinical trials, and to understand the molecular basis of T-cell responses.
In the spirit of a staged evaluation approach it is mandatory to study the effects of treatments for patients who have actively chosen them, since free choice is part and parcel of a potentially important therapeutic step [ 21].
