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This management of variation allows the organization to achieve economies of scope and provides the capability of mass customization where every market is treated as a niche.
In addition, we show how the strategy can be applied to conveniently define adaptive sample-specific boundaries between balanced copy number, losses, and gains to facilitate management of variation in tissue heterogeneity when calling copy number changes.
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A main problem of previous studies was the management of variations of insulin therapy during follow-up, which becomes more relevant with a longer observation; some studies (2, 4) analyzed baseline therapy, missing relevant information, while another (3) applied questionable statistical models, using therapies during follow-up as if they were baseline variables.
Despite intensive monitoring and management, causes of variation in key demographic parameters remain poorly understood.
By combining soil data with extensive botanical inventories, we investigated how farmers' use and management of soil variation results in differences in the structure, diversity and the floristic composition of homegardens in Central Amazonia.
This sib-test provided a challenging test for the management of genetic variation but it is also very relevant as it in such circumstances that the use of genomic data in breeding value estimation is of greatest value.
Besides these adaptations at the level of the genome, management of antigenic variation requires networking of VSG gene expression with other trypanosome phenotypes, including growth, differentiation, and, beyond the individual infection, unpredictable transmission into a very broad range of hosts, some of which will be partially immune.
The management of genetic variation has also been circumscribed to crop/livestock diversity, the impact of GMOs, and the occasional assessment of genetic erosion in endangered species with small or fragmented populations (GBO Secretariat of the Convention on Biological Diversity 2010).
Due to the growth of electric end-uses, the management of the variations in time of the electric power demand has become essential, especially in the residential sector.
For car and aircraft industries, the management of geometrical variations has become an important issue in product design process and concurrent engineering.
The main objective of this work is to provide a simple and fast tool that can be used as a component of wider models of DHNs to improve the control strategies and the management of load variations.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com