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In contrast, freeze-drying (i.e. lyophilization) of the cells should theoretically substantially decrease the risks associated with storage at ultra-low temperatures, thus simplifying the procedure, reducing costs and allowing for better management of sample storage and transport.
Doctors Maria Saarela and Jaana Mättö are gratefully acknowledged for recruiting HC study subjects and management of sample collection.
The respondents received no incentives for completing and submitting their answers, and no personal information was provided (management of sample through the panel owned by a third party vendor).
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SAK contributed to the study design, management of samples, and drafting the manuscript.
MCS contributed to study design and contributed to the management of samples obtained through the University of Melbourne.
These issues are exacerbated by the persistent weakness in the management of samples and results by practices and laboratories.
We applied the digital repository to the integrated management of samples, patients and medical history in the BIT-Gaslini biobank.
We used a purposive direct sampling strategy to select the key members of staff that were involved in the management of samples, analysis and communication systems.
In spite of previous rounds, where errors were mainly due to technical errors, during the VII round all errors were caused by suboptimal management of samples [ 14, 16].
MCS contributed to study design, contributed to the management of samples obtained through the Australian site of the BCFR, and helped to draft the manuscript.
However, further work is required to move these tools from research laboratories to clinical practice, mainly by improving standardization of the process and management of samples and derived material before analysis.
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