These findings have important implications for our understanding of these life history types, and also for the conservation and management of declining, threatened, or endangered stream-type Chinook salmon populations in the US and Canada.
Population genetics plays an increasingly important role in the conservation and management of declining species, particularly for defining taxonomic units.
When used and interpreted appropriately, however, genetics can provide critical insights into the biology and management of declining species.
However, for nonmodel species with large and complex genomes, inferring genetic hallmarks of disease susceptibility from a limited number of loci may be the only feasible approach and can be a useful tool for genetic management of declining populations.
Patients with CKD (stages 1 4) had been referred (in line with clinical practice guidelines at the time) to secondary care for investigation and management of declining renal function.
It is used for timely detection and management of declining renal function, to adjust the dosage of renally excreted drugs appropriately, and to avoid nephrotoxic drugs [ 1, 8, 9].
