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Of those initially managed with watchful waiting, 15 later received treatment with curative intent and 184 received palliative treatment.
It is vital that patients managed with watchful waiting are regularly followed up by their physician to monitor any progression (or remission) of the condition.
At the time of the questionnaire, 383 men were thus managed with watchful waiting, 635 received palliative treatment and for 219 treatment with curative intent was registered as the last treatment received.
31 It has been proposed that some small PTCs be reclassified as non-cancers 2 3 10 or that the most biologically indolent tumours be managed with watchful waiting.
On the other hand, large cohort studies of patients managed with watchful waiting did show correlations with a positive fusion status being associated with reduced survival (Attard et al, 2007; Demichelis et al, 2007).
The 2003 AUA Guideline states that patients with mild BPH symptoms (AUA Symptom Index <7) and those with moderate-to-severe symptoms (AUA Symptom Index ≥8) that do not interfere with quality of life should be managed with watchful waiting (AUA 2003).
Similar(54)
AS differs from watchful waiting because definitive treatment is used in patients managed with AS when there is evidence that the patient is at an increased risk for disease progression [4, 5].
Due to concerns about the risks of revision, people who are expected to outlive a primary THR are often managed with non-surgical interventions, such medication to alleviate pain and to delay or prevent the need for surgery; collectively these interventions have been referred to as 'watchful waiting' (WW).
Among 86,298 men with stage I and II prostate cancers reported to the National Cancer Data Base (NCDB) with 1998 diagnoses, 39% were treated with surgery, 42% received radiation, 18% were managed conservatively (watchful waiting with or without hormone therapy), and 1% received other specified therapy.
Interestingly, high expression of PDGFRβ in the stroma of adjacent normal prostate tissue was also associated with a significantly reduced survival in patients managed by watchful waiting (15-year P-EFS was 68±5% and 41±9% in the two groups) (Figure 4 B).
Patients with aggressive disease would be encouraged to consider early intervention whereas those with cancer that are not likely to progress could safely be managed by watchful waiting.
Related(20)
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