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Too often, he told me, he would sit in his office and be "telling you stuff too little, too late — that if you'd been able to lose a little weight or if your diabetes had been managed more aggressively, then it would have dramatically changed your destiny, which is now to go downstairs and have open heart surgery".
After achievement of LDL cholesterol goals, non HDL cholesterol can be managed more aggressively by lowering LDL cholesterol or by using strategies that target a reduction in very-low-density lipoprotein cholesterol.
It is likely that women who conceive through ART receive close follow-up and are managed more aggressively [ 11].
As HE is a frequent complication of TIPS (median cumulative 1-year incidence: 10-50%), it was likely sought after and managed more aggressively in these patients [ 12].
Given these findings and the poor efficacy of current treatment modalities, it seems that patients with poorly differentiated ECs and high sHE4 levels could be managed more aggressively, using contemporary therapeutic options, than those with low sHE4 levels.
These factors may limit the generalizability of our results to health care systems in which children are admitted earlier in their critical illness course and are managed more aggressively.
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If, on the other hand, future water inflows can be well characterized, water supplies can be managed much more aggressively.
A shift in the paradigm of treatment is needed and should aim at definite objectives, as already dictated by the diabetes community: "Diabetes must be prevented sooner and diagnosed earlier (48)." "…And once diagnosed, all types of diabetes must then be managed much more aggressively" (49).
Governor Jerry Brown recently indicated the need to do more to protect and manage groundwater more aggressively.
Fassel is simply managing them more aggressively.
I stayed aggressive and I managed to play more aggressively in the second set.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com