Sentence examples for managed by dose from inspiring English sources

CONCLUSION: Weekly low-dose carboplatin and paclitaxel has significant activity in both platinum-sensitive and platinum-resistant recurrent ovarian cancer with acceptable toxicity that is easily managed by dose adjustment.

In most cases, hematologic toxicities were managed by dose reduction.

These were not problematic and were effectively managed by dose modification, supportive care and pharmacological interventions.

Significant proteinuria was managed by dose interruption and/or modification with no indication for renal support.

Of the 257 AEs (in 217 patients) managed by dose reduction, 247 (96%) resulted in continuation of tocilizumab therapy.

In the majority of cases, hematologic toxicity was managed by dose reduction and symptomatic treatment with hematopoietic growth factor.

A few subjects taking higher chronic benzodiazepine dosages experienced breakthrough anxiety or withdrawal symptoms, which were well managed by dosing flumazenil immediately before the anesthetic agent and by immediate posttreatment benzodiazepine administration.

Hematological toxicity could be easily managed by dose-reductions.

Upper limit pH control was managed by dosing acid extractant back into the fermentation broth, at less than 1 mL day−1 on average, as the applied current scheme was designed to avoid excess electrolysis.

Twenty-nine percent of cytopenias were managed by drug dose delay and 9% by dose reduction.

Sunitinib-related adverse events are frequently managed by a dose reduction from 50 mg oral daily to 37.5 or 25 mg (Sutent SmPC), suggesting that lower doses of sunitinib are better tolerated than the recommended dose, which would presumably also reduce adverse event management costs.