Sentence examples for manageable reduction from inspiring English sources

IMF staff looked at the likely impact of spending cuts and found that, in normal times, every 1% of GDP of spending cuts reduced the overall size of the economy by 0.5%, a painful but manageable reduction.

Anatomic alignment of the ulnar fracture with restoration of the trochlear notch typically allows for a manageable reduction of the proximal radiocapitellar joint and, consequently, a satisfactory result.

Pneumonitis was grade 2 or lower, and manageable with dose reduction or interruption of treatment.

Overall, adverse events were reversible and manageable with dose reduction, dose delay or treatment interruption and with symptomatic treatment.

Adverse events reported rarely required permanent vemurafenib discontinuation and were generally manageable with dose reduction or interruption 25.

Most EVE-associated AEs occur soon after initiation of therapy, are typically of mild or moderate severity, and are generally manageable with dose reduction and interruption.

In addition, PN associated with ixabepilone was shown in monotherapy studies to be generally reversible and often manageable with dose reduction [ 15– 17].

(32, 33) Diarrhea was mostly manageable but dose reduction or therapy discontinuation was often needed for the patient experienced higher grade diarrhea.

AE rates at 8 months in the four single-arm studies are provided in Table 2. Dasatinib was generally well tolerated in all four studies; overall, toxicities were manageable through dose reduction or interruption and resumption at a lower dose.

Peripheral neuropathy was cited as the reason for dose modification in 10 patients; as only 59(9 %) patients discontinued treatment due to peripheral neuropathy, this toxicity was generally manageable with dose reduction or delay.

So far, it appears to have positive effects, with a safety profile comparable to that of lenalidomide alone, and is manageable by dose reductions (Fig. 1 91.