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The screening was by two-view mammography at first screen, with number of views thereafter dependent on breast density.
In East Anglia, 4.1% of women screened in the first screening round and eligible for a second screen underwent false-positive mammography at first screen.
With technical improvements to the programme and women's increased familiarity with it, reduced reattendance and increased risk of cancer may be less associated with false-positive mammography at first screen.
We quantify the magnitude of the increased risk of interval cancer, and extend these investigations to determine whether false-positive mammography at first screen increases the risk of cancer detected at second screen.
Women undergoing false-positive mammography at first screen were less likely to reattend for subsequent screens than were nonassessed women, yet they were more likely to develop interval cancers or cancers at second screen, and their cancers were larger.
After adjusting for age, symptom status, family history, past history of mammography (at first round) and time since screen (at subsequent round), HRT users had higher risk of having a false negative (first round: odds ratio [OR], 1.99; 95% confidence interval [CI], 1.4 2.9 and subsequent round: OR, 2.29; 95% CI, 1.4 3.8).
Similar(54)
This study aimed to evaluate the frequency of risk factors of breast cancer and assess the women' age referred to mammography center at first screening mammogram in Bandar Abbas county, Iran.
Screening in the trial is by two-view mammography at the first screen, with single view thereafter unless otherwise indicated.
At the time of recruitment, nine of the ten screening centres used two-view mammography at the first screening round and single-view mammography at subsequent rounds; one centre used two-view mammography for all screens.
To do this, we conducted a cluster analysis to determine the characteristics of women presenting for opportunistic screening, starting first with a model containing all variables in Table 1, mammography history, age at first mammogram and motivators for attending screening, and sequentially excluding variables with the least association with mammography history (Table 2).
Two-view mammography is performed at first screening rounds, while at subsequent rounds a single view is made.
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