Sentence examples for mammary structures and from inspiring English sources

Moreover, adequate study of toxicant exposures during critical windows of mammary gland development are necessary given the higher susceptibility to environmental toxicants in developing mammary structures and that dieldrin readily crosses the placental barrier and is excreted in breast milk leading to its accumulation in fetal and neonatal adipose tissues including the mammary glands [21] [23].

At 3 weeks, there was a significant HFD-induced increase in recruitment of eosinophils to all mammary structures and of mast cells to large ducts.

Deletion of Elf-5 can lead to disorganized mammary structures and collapsed lumens, suggesting that this decrease in expression could be playing a role in the observed phenotype [ 32].

At both 4 and 10 weeks on diet, there were significant increases in epithelial cell proliferation in HFD-fed mice, with the highest proliferation seen at 10 weeks in normal mammary structures and hyperplastic lesions.

This scenario would imply that alteration of hair form, mammary structure and any possible effect on tooth morphology, are 'off-target' consequences of pleiotropic EDAR action.

Studies using three-dimensional mammary culture models have reported that constitutive CSF1 receptor signaling causes uncontrolled proliferation and altered E-cadherin mediated adhesion, thereby disrupting normal mammary structure and development [ 13].

The shortened period of lactation found by Gladen and Rogan (1995) in Mexican agriculture-based mothers may be reflective of poor mammary structure and not solely to blood levels of DDE or other pesticides at the time of infant delivery.

More recently, it has been demonstrated that ERα+ human breast cells are able to grow and generate colonies in vitro and mammary structures in vivo that are restricted to the luminal lineage (Honeth et al. 2014).

The results showed that the engineered ALDHlow cells had regenerated the same bilayered mammary structures as seen previously and that immunoreactive human β-CASEIN was clearly evident in the lumen of some of the regenerated structures (1 to 3 per xenograft) (Figure 3c).

Other groups transplanted mixed populations and inferred that the mammary gland contains progenitors that can give rise to mammary structures of different sizes and morphological characteristics [ 12, 13].

Using mammary fat pad transplantation assays, we found that H2BGFP+/CD24+/CD29lo cells contain a population of multipotent progenitors that give rise to mammary structures capable of differentiation and lactation, but which cannot be serially transplanted.