Sentence examples for mammary development the from inspiring English sources
In addition to regulating mammary development, the Wnt/β-catenin pathway is also associated with breast cancer.
To determine whether MUC1-CD has effects on mammary development, the inguinal mammary glands from four mice of 8-wk-old virgin females for each group were excised and compared between MMTV-GFP-MUC1-CD transgenic mice and wild-type littermates.
For mammary development, the signalling interactions in the placode epithelium are particularly poorly described.
Although a plethora of data suggests a central role for macrophages during mammary development, the precise mechanisms remain unknown.
During mammary development, the MaSC has been proposed to divide asymmetrically to produce basal/myoepithelial cells as well as luminal progenitors (LumProg), which have more restricted proliferative and differentiation capabilities [ 5].
Upon devising a microarray strategy to identify novel regulators of mammary development, the investigators observed the mammary epithelium in vivo of laboratory mice genetically altered to lack GATA-3.
The mammary end bud is the icon of the ductal phase of mammary development in the rodent, at one and the same time the most familiar and the most mysterious of structures.
Ovariectomy of prepubertal dairy heifers curtails further mammary development, where the earlier in life the procedure is performed, the more drastic is the result [ 25].
Additionally, these cells have been analyzed through the different stages of mammary development and the percentage of each morphotype calculated.
This review will provide an update on the Hh signalling pathway and its role in the regulation of normal mammary development and the aetiology of breast cancer.
More specifically, in addition to dissecting the molecular mechanisms underlying mammary development and the initial steps of mammary neoplastic transformation, mouse models have shown that activation of a particular pathway is reflected in specific histologic patterns [ 6, 7].
