Sentence examples for mammals we generated from inspiring English sources

To address the biological function of the SUMO pathway in mammals, we generated mice deficient for the SUMO E2-conjugating enzyme Ubc9.

To determine the molecular function of the second step of hypusine modification in mammals, we generated a mouse strain enabling conditional knockout of Dohh (B6.Dohhtm1bal).

By assaying CTCF binding in matched tissues of six diverse mammals, we generated high-resolution in vivo maps of CTCF evolution.

As MGS is the only enzyme able to synthetize glucose polymers in mammals, we generated an MGS knockout mouse (MGS KO, see Fig. S1 (Supporting information) and Materials and Methods for details) and evaluated the relevance of MGS for the formation of these age-dependent PGBs in mouse brain.

To determine whether dCTCF is involved in imprinted regulation in Drosophila as it is in mammals, we generated a dCTCF mutant allele with severe reduction in dCTCF expression and tested its effects on the expression of the imprint marker gene, garnet, on the Dp(1 f LJ9 mini-X chromosome.

To compare the structures of apo- and holo-CCT particles from the psychrophilic fish to those of the mesophilic mammal, we generated two-dimensional average images by negative-stain EM.

In order to understand the role of ETP in mammals, we have generated gene trap mutant mice for Asx-like 2 (Asxl2).

Because in mammals no physiological function has been reported so far, we generated Kv10.1-deficient mice to elucidate the functional role of Kv10.1 in the brain.

To answer these questions, we generated a bichromatic fluorescent splicing reporter system for mammals using FGFR2 gene as a model.

To answer these questions, we generated an original bichromatic fluorescent splicing reporter system for mammals using fibroblast growth factor-receptor 2 (Fgene) gene as model.

We generated a high confidence list of putative binding sites using an approach previously utilized in identifying motifs in mammals [15].