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If a teratoma contains fetal tissue or neuroendocrine tissue, it is defined as immature and malignant with a poor prognosis.

High-grade serous carcinoma is highly malignant with a 5-year survival rate of less than 30%.

Presacral tumors are most frequently benign, occasionally malignant with a slow growth.

Core biopsy was definitive in 79.8% cases (57% benign 22% malignant) with a PPV of 100% and NPV of 99.0%.

It is probable that this different origin of SSEM determines its predominantly benign behavior, in contrast to CSEM, which is malignant with a high metastatic potential [ 20],[ 25].

Each observer evaluated MR imaging features and diagnosed the lesion as benign or malignant with a five-point confidence rating (1, definitely benign; 2, uncertain benign; 3, undetermined; 4, uncertain malignant; and 5, definitely malignant).

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ACTH secretion occurs only rarely, presenting with features of Cushing's syndrome, but more than 95% are malignant with an average age at diagnosis of 50 55 years and an equal sex distribution [ 1].

One of the greatest challenges in screening mammography is the need to balance high sensitivity for abnormalities which could prove to be malignant with an acceptably low recall rate for assessment.

Differential expression of the five genes mentioned above was observed among benign, pre-malignant and malignant tumors, with a tendency to higher expression in the more malignant ones, with Pttg1 being expressed only in the latter group.

Pathological examination revealed that six (33.3%) tumours had other carcinoma components concomitantly and that two (11.1%) were malignant MA, with a surprisingly high proportion of malignant case.

Cutaneous malignant melanoma is responsible for 1% of all malignant tumors with a rising incidence in the Caucasian population [ 1].

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