Sentence examples for malignant transformations by from inspiring English sources

In the future, we hope to be able to identify several dominant factors associated with malignant transformations by applying a time-dependent sensitivity analysis [26] to our proposed model.

These results are comparable with reported malignant transformations by inorganic arsenic in other cell lines [ 21].

TRAIL-induced apoptosis of transformed/dysplastic cells is independent of p53 status [ 34, 44], hence, TRAIL may act as a substitute guardian against malignant transformation by eliminating transformed cells during the initial genesis OPM.

E6 is able to immortalize cells and induce malignant transformation by inactivating p53.

Among the animal viruses that cause malignant transformation by integration of proviral DNA are several families of DNA viruses and one large family of RNA viruses, the Retroviridae.

Lazaris-Karatzas, A., Montine, K.S. & Sonenberg, N. Malignant transformation by a eukaryotic initiation factor subunit that binds to mRNA 5′ cap.

MHC class I molecules play a central role in the immune response against a variety of cells that have undergone malignant transformation by shaping the T cell repertoire and by presenting peptide antigens from endogeneous antigens to CD8+ cytotoxic T cells.

In general, gammaretroviruses like XMRV induce malignant transformation by insertional mutagenesis, so that malignant cells in a tumor are all clonally infected.

A direct role for NPM-ALK in cellular transformation has been shown both in vitro and in vivo, and such studies have shed light on the mechanism of malignant transformation by this oncoprotein [18], [19].

However, the proposal that cell fusion can initiate malignant transformation by no means excludes other mechanisms.

These genes help prevent malignant transformation by keeping cellular proliferation and differentiation within normal ranges.