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Among these, TGF-β, VEGF and TNFα are known to promote the malignant traits of CRC cells by inducing EMT (20).
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The Hippo transducer pathway has been shown to confer malignant traits on breast cancer cells.
Exposure of cells to UV harms their DNA and this can lead to cell death (if damage is excessive) or cellular transformation (if damage induces genomic mutations that confer neoplastic or malignant traits to cells).
EMT has a central role in embryogenesis and is also involved in acquisition of malignant traits in carcinoma cells.
To our knowledge, no study has specifically focused on linking expression of malignant traits (i.e. EMT, WNT activity, stemness signatures) in colon cancer cell lines to response to therapy.
This high degree of biological plasticity makes cancer cells an elusive target for most therapies, and urges to define specific biological traits of malignant cells that could be utilized for tailored pharmacological approaches.
Chemodectoma may manifest traits of a malignant tumour or of a benign tumour [ 1, 3].
Traits of the Scientist-Entrepreneur.
Furthermore, many traits of var.
Learn the physical traits of Cancer.
Learn the physical traits of Leo.
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