Sentence examples for malignant stages of from inspiring English sources
Further, the phospho-serine-15 levels of p53 were drastically downregulated in benign and malignant stages of breast cancer (Figure S4A and B) implicating that once SMAR1 function is disrupted, p53 is no more stabilized.
Our study suggests that the present screening programme for cervical cancer is efficient in detecting (pre) malignant stages of squamous cell carcinoma, but fails to detect (pre) malignant stages of adenocarcinoma (Sasieni and Adams, 2001).
In some cancer cells a relation between a decreased autophagy and malignant stages of the disease has been found.
Additional molecular alterations in DCIS are thought to give rise to the malignant stages of invasive and metastatic carcinoma.
In this study, we examined the expression of β2M at different malignant stages of oral cavity squamous cell carcinoma (OCSCC).
We finally identified and sorted the CD44/Sca1+ cells from mammary epithelial/tumor cells of MMT mice at premalignant and malignant stages of tumorigenesis.
The expression level of differentiation markers in the stroma might be dependent on the malignant stage of the adjacent epithelial cells and may account for the contradictive reports of the differentiation marker levels in CAFs.
Despite using different platforms (cDNA arrays versus oligonucleotide arrays versus SAGE), several studies have demonstrated that the transition from the premalignant stage of DCIS to the malignant stage of IDC is associated with quantitative, rather than qualitative, differences in gene expression [ 10, 11].
Although most patients with urinary bladder cancer present with noninvasive and low-malignant stages of the disease, about 20% eventually develop life-threatening metastatic tumors.
Accordingly, the absence of Atm has a modest impact on the pre-malignant stages of this tumorigenesis model.
Collectively, we conclude from the above data that senescence at the pre-malignant stages of K-RasV12-driven lung tumorigenesis is not associated to a detectable DNA damage response and it is independent of the status of Atm.
