Sentence examples for malignant stage from inspiring English sources

The pathogenesis of HCC is also believed to be a long-term process which begins from the pre-malignant stage to the dysplastic stage and finally proceeds to the malignant stage (Thorgeirsson and Grisham, 2002).

As long as I catch it early enough and I'm taking the precautionary actions to prevent them getting to a malignant stage then I'm happy with that".

The chapter provides immunologic evidence and molecular biologic evidence to show that MUC18 may be a possible diagnostic marker for monitoring the progression of prostate cancer from premalignant stage (PIN) to malignant stage and to metastasis to other organs.

Moreover, silencing of Bmi1 by siRNA leads to the death of cancer cells specifically [12], suggesting that its activity is also essential for viability during the malignant stage.

In summary, gene expression profiling during neoplastic progression of MOSE cells revealed that cytoskeleton associated genes were significantly impacted as cells transitioned from a benign to a malignant stage.

In the present study, we have identified genes and their functional categories that were altered as MOSE-derived cells transition from an early, pre-malignant, to a highly malignant stage.

Now, it is widely accepted that cancer evolves progressively from normal cells to malignant stages.

Further, the phospho-serine-15 levels of p53 were drastically downregulated in benign and malignant stages of breast cancer (Figure S4A and B) implicating that once SMAR1 function is disrupted, p53 is no more stabilized.

They found increased Sept9 levels in hyperplastic and malignant stages.

The dynamics of mRNA expression is a blueprint of cancer progress from benign to malignant stages.

In terms of TNM stage, 100% (n=184) showed strong staining in the more malignant stages (III, IV), whereas 100% (n=72) presented with weak staining at less malignant stages (I, II).