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The malignant rate in this series was 43.1% (22/51).
In Table 1, the person-time malignant rate was also estimated with consideration given to the duration of follow-up.
Our recorded annual malignant rate of 3.38% is higher than the rate documented in the literature (0.69%-2.03%) [ 9- 11].
The Kaplan-Meier estimates of the 3-year cancer-free rate of epithelial dysplasia and VH were less than 80%, which meant that the malignant rate of these two OPMDs were higher than 20%.
Similar(56)
Although the AGC-rate reported here is one of the lowest described, our series presents the highest, mostly early stage, malignant rates with predominantly endometrial lesions, despite the use of cotton swabs.
In our study, hyperkeratosis or epithelial hyperplasia, epithelial dysplasia had a malignant transformation rate from 8% to 24%, and the annual rate is 3 8 per 100 persons-year.
Cancer site-specific percentages of unstaged disease were calculated by dividing the age-adjusted malignant incidence rate of unstaged disease by the total age-adjusted incidence rate.
We also took follow-up duration into account to estimate the malignant transformation rate and to evaluate related factors of malignancy.
In previous studies, the malignant transformation rate of hyperkeratosis or epithelial hyperplasia, epithelial dysplasia was reported to be 10 20% and the annual rate was 1.4%7%% [ 5, 6, 12, 17].
Malignant transformation rate.
Enoz et al. [14] reported a malignant transformation rate for head and neck schwannoma of 8 10%.
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