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The second most frequent second malignant neoplasms have been soft-tissue sarcomas [3].
Nonocular second malignant neoplasms have occurred almost exclusively in children with bilateral disease, who constitute only 25% of cases.
In children previously irradiated for retinoblastoma, 70% of second malignant neoplasms have occurred in the field and 30% outside the field of radiation [1].
A variety of second malignant neoplasms have been reported in the literature, including osteosarcoma, fibrosarcoma, skin carcinomas, malignant melanomas, rhabdomyosarcomas, acute lymphoblastic leukemia, and sinonasal carcinoma, but few reports indicate the frequency of development of Ewing's sarcoma after retinoblastoma [6].
Prior to treatment, an individual's breast cancer is placed within a "stage" ranging from 0 to IV. Staging breast cancer helps to document the severity of the disease and whether the malignant neoplasms have metastasized to other parts of the body or remained in their local tissue.
In Japan, malignant neoplasms have the highest mortality rate, surpassing cerebrovascular and heart diseases in 1981.
Similar(53)
Globally, the proportion of deaths attributed to malignant neoplasms has risen from 12.49 % of all deaths in 2002, when they ranked third in worldwide causes of death, to 23.3 % today [14 , 15.
Malignant neoplasms had the highest mortality rate (30.8%) followed by aortic aneurysm and pneumonia.
Malignant neoplasms had the highest mortality rate followed by aortic aneurysms and pneumonia.
The presence of a high number of infiltrating CD1a+cells in malignant neoplasms has been reported to be associated with an improved prognosis, reduced tumour recurrence and fewer metastases.
The over-expression of these proteins and their known functions in malignant neoplasms has led to the development of HDAC inhibitors (HDI) as new anti-neoplastic drugs.
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