Sentence examples for malignant mutation from inspiring English sources
Multiple personalities: The three colors of these cells, all taken from the same aggressive breast-cancer tumor, represent different cell populations, each with its own distinct malignant mutation.
Moreover, polymorphisms of some genes coordinated in the attack to develop the mucosa cells malignant mutation.
One very malignant mutation is R723G, where about 2/3 of total MYH7-mRNA and β-myosin are mutated.
In patients with mutation R723G, a malignant mutation appears benign at young age (patients H71 and H72), while mutation R719W is already very severe in young patients.
Constant constriction suffocates the cells and promotes malignant mutations.
Either way, p53's action helps short-circuit tumor formation by preventing cells that have suffered malignant mutations from continuing to grow.
Is this malignant myosin mutation directly disrupting myofibril assembly through molecular level changes, or is this disarray a secondary effect of changes in global cardiac function and loading?
For the search, the three keywords "Malignant Hyperthermia", "Mutation" and "Ryanodine Receptor Calcium Release Channel" were used; the operator was "AND".
Characteristics were also stratified according to the presence of malignant tumors, mutation type and genotype, and compared using Pearson's χ and Mann–Whitney U tests for categorical and continuous variables, respectively.
Although mutations in the Axin gene have been detected and implicated in a few types of malignant tumors, the mutation rate is low and sporadic, and the hot spots of the mutations have not been identified in any specific type of malignant tumor [ 6- 11].
Deletion of the p16INK4a/ p14ARF locus is found in both benign and malignant meningiomas, while mutation of the p53 tumor suppressor gene is uncommon.
